Teeing Up Transcription on CpG Islands
نویسنده
چکیده
Eukaryotic cells use elaborate molecular mechanisms to rapidly activate signal-dependent gene expression. New work provides fresh insights into these mechanisms by demonstrating that CpG islands in promoters are nucleosome-destabilizing elements and can facilitate the establishment of an unusual poised transcriptional state (Ramirez-Carrozzi et al., 2009; Hargreaves et al., 2009).
منابع مشابه
Study of promoter CpG island hypermethylation of cyclindependent kinase inhibitor gene p21waf1/cip1 on some breast carcinoma cell lines
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ورودعنوان ژورنال:
- Cell
دوره 138 شماره
صفحات -
تاریخ انتشار 2009